Leucine

Abbrev. L Leu
Full Name Leucine
Side chain type
hydrophobic
Mass
131.17
pl
6.01
pK1(α-COOH)
2.16
pK2(α-+NH3)
2.33
pKr (R) 9.74

Side chain -CH2CH(CH3)2
Hydro- phobic
yes
Polar
no
Charged
no
Small
no
Tiny
no
Aromatic or Aliphatic
Aliphatic
van der Waals volume
124
Codon
UUA, UUG, CUU, CUC, CUA, CUG
Occurrence in proteins (%)
9.1

Remarks: Essential for humans. Behaves similar to isoleucine and valine. See isoleucine.

Leucine is one of the 20 most common amino acids and coded for by DNA. It is isomeric with isoleucine. Nutritionally, in humans, leucine is an essential amino acid.

Leucine is the most common amino acid found in proteins, and is essential for optimal growth in infancy and childhood and for nitrogen equilibrium in adults. It is suspected that Leucine plays a part in maintaining muscles by equalizing synthesis and breakdown of proteins.

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